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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLK1
All Species:
14.85
Human Site:
S174
Identified Species:
32.67
UniProt:
Q9UKI8
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKI8
NP_036422.3
766
86700
S174
A
I
R
S
P
Q
N
S
H
S
H
S
T
P
S
Chimpanzee
Pan troglodytes
XP_001141231
787
89005
Q174
I
S
D
Y
F
E
Y
Q
G
G
N
G
S
S
P
Rhesus Macaque
Macaca mulatta
XP_001084145
718
81923
A174
D
L
T
M
L
K
L
A
A
L
E
S
N
K
I
Dog
Lupus familis
XP_535959
766
86670
S174
A
I
R
S
P
Q
N
S
H
S
H
S
T
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0V0
766
86605
S174
A
I
R
S
P
Q
N
S
H
S
H
S
T
P
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515053
718
81881
A174
D
L
T
M
L
K
L
A
A
L
E
S
N
K
N
Chicken
Gallus gallus
XP_426581
764
86358
S175
A
I
R
S
P
Q
N
S
H
S
A
P
S
S
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q90ZY6
756
85436
A175
S
P
Q
N
S
H
S
A
P
G
A
I
V
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624065
793
90042
A202
P
P
A
S
T
Q
P
A
G
S
M
V
S
K
Q
Nematode Worm
Caenorhab. elegans
P34314
965
109255
S219
Q
Q
Q
S
Q
Q
Q
S
A
Q
Q
P
Q
Q
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39238
688
78131
S174
V
A
P
V
S
A
A
S
Q
L
D
A
S
D
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
93.5
99.4
N.A.
98.1
N.A.
N.A.
91.5
94.1
N.A.
83.2
N.A.
N.A.
46.4
37.9
N.A.
Protein Similarity:
100
97.3
93.7
99.7
N.A.
99.2
N.A.
N.A.
92.8
95.8
N.A.
89.4
N.A.
N.A.
61.2
50.8
N.A.
P-Site Identity:
100
0
6.6
100
N.A.
100
N.A.
N.A.
6.6
66.6
N.A.
0
N.A.
N.A.
20
26.6
N.A.
P-Site Similarity:
100
20
26.6
100
N.A.
100
N.A.
N.A.
33.3
73.3
N.A.
33.3
N.A.
N.A.
33.3
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
37
10
10
0
0
10
10
37
28
0
19
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
0
10
0
0
0
0
0
0
0
10
0
0
10
0
% D
% Glu:
0
0
0
0
0
10
0
0
0
0
19
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
19
19
0
10
0
0
0
% G
% His:
0
0
0
0
0
10
0
0
37
0
28
0
0
0
0
% H
% Ile:
10
37
0
0
0
0
0
0
0
0
0
10
0
0
10
% I
% Lys:
0
0
0
0
0
19
0
0
0
0
0
0
0
28
0
% K
% Leu:
0
19
0
0
19
0
19
0
0
28
0
0
0
0
0
% L
% Met:
0
0
0
19
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
37
0
0
0
10
0
19
0
10
% N
% Pro:
10
19
10
0
37
0
10
0
10
0
0
19
0
28
10
% P
% Gln:
10
10
19
0
10
55
10
10
10
10
10
0
10
10
28
% Q
% Arg:
0
0
37
0
0
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
10
10
0
55
19
0
10
55
0
46
0
46
37
19
37
% S
% Thr:
0
0
19
0
10
0
0
0
0
0
0
0
28
0
0
% T
% Val:
10
0
0
10
0
0
0
0
0
0
0
10
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _